The ATP-sensitive potassium channel

From the Nichols lab: The ATP-sensitive potassium channel is a key link between metabolism of the cell and its electrical activity. The structure is modeled on a bacterial homolog, and shows the ATP binding site to which ATP binds, favoring the closed state of the channel. (KATP channels as molecular sensors of cellular metabolism. Nichols, C.G., Nature. 2006, 440:470-6). For more on the biophysics of ion channels, visit the Nichols lab web site http://www.nicholslab.wustl.edu/

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